2YPQ
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with tryptophan and tyrosine bound
Summary for 2YPQ
Entry DOI | 10.2210/pdb2ypq/pdb |
Related | 2YPO 2YPP |
Descriptor | PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE AROG, TYROSINE, MANGANESE (II) ION, ... (9 entities in total) |
Functional Keywords | shikimate pathway, transferase, aromatic amino acid biosynthesis, allostery |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Total number of polymer chains | 2 |
Total formula weight | 103283.78 |
Authors | Blackmore, N.J.,Reichau, S.,Jiao, W.,Hutton, R.D.,Baker, E.N.,Jameson, G.B.,Parker, E.J. (deposition date: 2012-10-31, release date: 2013-01-09, Last modification date: 2023-12-20) |
Primary citation | Blackmore, N.J.,Reichau, S.,Jiao, W.,Hutton, R.D.,Baker, E.N.,Jameson, G.B.,Parker, E.J. Three Sites and You are Out: Ternary Synergistic Allostery Controls Aromatic Aminoacid Biosynthesis in Mycobacterium Tuberculosis. J.Mol.Biol., 425:1582-, 2013 Cited by PubMed: 23274137DOI: 10.1016/J.JMB.2012.12.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.76 Å) |
Structure validation
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