2YPK

Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms

Summary for 2YPK

Entry DOI	10.2210/pdb2ypk/pdb
Related	2YPL
Descriptor	HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN, BETA-2-MICROGLOBULIN, KF11 P24 GAG PEPTIDE, ... (4 entities in total)
Functional Keywords	immune system, micropolymorphism
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Membrane; Single-pass type I membrane protein: P18465 Secreted: P61769 Capsid protein p24: Virion (By similarity). Integrase: Virion. Matrix protein p17: Virion (By similarity). Matrix protein p17: Virion. Nucleocapsid protein p7: Virion (By similarity). Reverse transcriptase/ribonuclease H: Virion (By similarity): Q70XD7
Total number of polymer chains	3
Total formula weight	44524.63
Authors	Stewart-Jones, G.B.,Simpson, P.,Van Der Merwe, P.A.,Easterbrook, P.,Mcmichael, A.J.,Rowland-Jones, S.L.,Jones, E.Y.,Gillespie, G.M. (deposition date: 2012-10-30, release date: 2012-11-28, Last modification date: 2023-12-20)
Primary citation	Stewart-Jones, G.B.,Simpson, P.,Anton Van Der Merwe, P.,Easterbrook, P.,Mcmichael, A.J.,Rowland-Jones, S.L.,Jones, E.Y.,Gillespie, G.M. Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms. Proc.Natl.Acad.Sci.USA, 109:E3483-, 2012 Cited by PubMed: 23161907 DOI: 10.1073/PNAS.1207896109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation