2YJ0

X-ray structure of chemically engineered Mycobacterium tuberculosis Dodecin

Summary for 2YJ0

Entry DOI	10.2210/pdb2yj0/pdb
Related	2YIZ
Descriptor	DODECIN, N-[2-({[5-(DIMETHYLAMINO)NAPHTHALEN-1-YL]SULFONYL}AMINO)ETHYL]-2-IODOACETAMIDE, COENZYME A, ... (7 entities in total)
Functional Keywords	flavoprotein, flavin binding protein, protein-engineering, putative storage protein, dodecin hybrid
Biological source	MYCOBACTERIUM TUBERCULOSIS
Total number of polymer chains	6
Total formula weight	55460.49
Authors	Vinzenz, X.,Grosse, W.,Linne, U.,Meissner, B.,Essen, L.-O. (deposition date: 2011-05-17, release date: 2011-10-12, Last modification date: 2024-11-13)
Primary citation	Vinzenz, X.,Grosse, W.,Linne, U.,Meissner, B.,Essen, L.-O. Chemical Engineering of Mycobacterium Tuberculosis Dodecin Hybrids. Chem.Commun.(Camb.), 47:11071-, 2011 Cited by PubMed Abstract: The suitability for chemical engineering of the highly symmetrical Mycobacterium tuberculosis dodecin was investigated, its inner cavity providing a large compartment shields introduced compounds from bulk solvent. Hybrids were obtained by S-alkylation of cysteine mutants and characterized by spectroscopic methods, including the crystal structures of wild type and biohybrid dodecins. PubMed: 21897938 DOI: 10.1039/C1CC12929E PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation