2YHO
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
Summary for 2YHO
Entry DOI | 10.2210/pdb2yho/pdb |
Related | 2C4P 2YHN |
Descriptor | E3 UBIQUITIN-PROTEIN LIGASE MYLIP, UBIQUITIN-CONJUGATING ENZYME E2 D1, ZINC ION, ... (5 entities in total) |
Functional Keywords | ligase, e2 ligase-e3 ligase complex, ring zinc-finger, ubl conjugation pathway |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Cytoplasm (Probable): Q8WY64 Cytoplasm: P51668 |
Total number of polymer chains | 8 |
Total formula weight | 103500.87 |
Authors | Fairall, L.,Goult, B.T.,Millard, C.J.,Tontonoz, P.,Schwabe, J.W.R. (deposition date: 2011-05-04, release date: 2011-06-29, Last modification date: 2023-12-20) |
Primary citation | Zhang, L.,Fairall, L.,Goult, B.T.,Calkin, A.C.,Hong, C.,Millard, C.J.,Tontonoz, P.,Schwabe, J.W. The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor. Genes Dev., 25:1262-, 2011 Cited by PubMed: 21685362DOI: 10.1101/GAD.2056211 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report