2Y85

CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE WITH BOUND RCDRP

Summary for 2Y85

Entry DOI	10.2210/pdb2y85/pdb
Related	2Y88 2Y89
Descriptor	PHOSPHORIBOSYL ISOMERASE A, SODIUM ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	isomerase, bifunctional enzyme, tryptophan biosynthesis, histidine biosynthesis, tim-barrel, aromatic amino acid biosynthesis
Biological source	MYCOBACTERIUM TUBERCULOSIS
Cellular location	Cytoplasm (By similarity): P60578
Total number of polymer chains	4
Total formula weight	104434.75
Authors	Kuper, J.,Geerlof, A.,Wilmanns, M. (deposition date: 2011-02-03, release date: 2011-03-02, Last modification date: 2023-12-20)
Primary citation	Due, A.V.,Kuper, J.,Geerlof, A.,Kries, J.P.,Wilmanns, M. Bisubstrate Specificity in Histidine/Tryptophan Biosynthesis Isomerase from Mycobacterium Tuberculosis by Active Site Metamorphosis. Proc.Natl.Acad.Sci.USA, 108:3554-, 2011 Cited by PubMed: 21321225 DOI: 10.1073/PNAS.1015996108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation