2Y4I
KSR2-MEK1 heterodimer
Summary for 2Y4I
Entry DOI | 10.2210/pdb2y4i/pdb |
Descriptor | KINASE SUPPRESSOR OF RAS 2, DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | transferase, ksr1 |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 2 |
Total formula weight | 81545.19 |
Authors | Brennan, D.F.,Barford, D. (deposition date: 2011-01-06, release date: 2011-01-19, Last modification date: 2023-12-20) |
Primary citation | Brennan, D.F.,Dar, A.C.,Hertz, N.T.,Chao, W.,Burlingame, A.L.,Shokat, K.M.,Barford, D. A Raf-Induced Allosteric Transition of Ksr Stimulates Ksr and Raf Phosphorylation of Mek Nature, 472:366-, 2011 Cited by PubMed: 21441910DOI: 10.1038/NATURE09860 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.46 Å) |
Structure validation
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