2Y00

TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND PARTIAL AGONIST DOBUTAMINE (CRYSTAL DOB92)

Summary for 2Y00

Related1DEP 2VT4 2Y04 2Y02 2Y03 2Y01
DescriptorBETA-1 ADRENERGIC RECEPTOR, CHOLESTEROL HEMISUCCINATE, HEGA-10, ... (6 entities in total)
Functional Keywordsg protein coupled receptor, seven-helix receptor, integral membrane protein, thermostabilising point mutations, gpcr, receptor
Biological sourceMELEAGRIS GALLOPAVO (TURKEY)
Total number of polymer chains2
Total molecular weight78249.1
Authors
Warne, A.,Moukhametzianov, R.,Baker, J.G.,Nehme, R.,Edwards, P.C.,Leslie, A.G.W.,Schertler, G.F.X.,Tate, C.G. (deposition date: 2010-11-30, release date: 2011-01-12, Last modification date: 2019-05-08)
Primary citation
Warne, A.,Moukhametzianov, R.,Baker, J.G.,Nehme, R.,Edwards, P.C.,Leslie, A.G.W.,Schertler, G.F.X.,Tate, C.G.
The Structural Basis for Agonist and Partial Agonist Action on a Beta1-Adrenergic Receptor
Nature, 469:241-, 2011
PubMed: 21228877 (PDB entries with the same primary citation)
DOI: 10.1038/NATURE09746
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers5 0.2% 4.0% 9.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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Molmil generated image of 2y00
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