2XS0
Linear binding motifs for JNK and for calcineurin antagonistically control the nuclear shuttling of NFAT4
Summary for 2XS0
Entry DOI | 10.2210/pdb2xs0/pdb |
Related | 1UKH 1UKI 2GMX 2H96 2XRW |
Descriptor | MITOGEN-ACTIVATED PROTEIN KINASE 8, NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total) |
Functional Keywords | transcription, transferase, mapk signaling pathways, linear binding motifs |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Cytoplasm: P45983 Q12968 |
Total number of polymer chains | 2 |
Total formula weight | 46453.23 |
Authors | Barkai, T.,Toeoroe, I.,Garai, A.,Remenyi, A. (deposition date: 2010-09-24, release date: 2011-09-28, Last modification date: 2023-12-20) |
Primary citation | Garai, A.,Zeke, A.,Gogl, G.,Toro, I.,Fordos, F.,Blankenburg, H.,Barkai, T.,Varga, J.,Alexa, A.,Emig, D.,Albrecht, M.,Remenyi, A. Specificity of Linear Motifs that Bind to a Common Mitogen-Activated Protein Kinase Docking Groove. Sci. Signal, 5:74-, 2012 Cited by PubMed: 23047924DOI: 10.1126/SCISIGNAL.2003004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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