2XNS

Crystal Structure Of Human G alpha i1 Bound To A Designed Helical Peptide Derived From The Goloco Motif Of RGS14

2XNS の概要

• エントリーDOI: 10.2210/pdb2xns/pdb
• 関連するPDBエントリー: 1KJY 1Y3A 2GTP 2IK8
• 分子名称: GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-1, REGULATOR OF G-PROTEIN SIGNALING 14, GUANOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
• 機能のキーワード: hydrolase-peptide complex, adp-ribosylation, arginine finger, gtp-binding, lipoprotein, nucleotide-binding, palmitate, signaling protein, transducer, protein-protein interface design, hydrolase/peptide
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 85518.16

構造登録者

Bosch, D.,Sammond, D.W.,Butterfoss, G.L.,Machius, M.,Siderovski, D.P.,Kuhlman, B. (登録日: 2010-08-05, 公開日: 2011-06-08, 最終更新日: 2023-12-20)

• 主引用文献: Sammond, D.W.,Bosch, D.E.,Butterfoss, G.L.,Purbeck, C.,Machius, M.,Siderovski, D.P.,Kuhlman, B.; Computational Design of the Sequence and Structure of a Protein-Binding Peptide.; J.Am.Chem.Soc., 133:4190-, 2011; PubMed: 21388199; DOI: 10.1021/JA110296Z

実験手法

X-RAY DIFFRACTION (3.41 Å)