2XIQ

Crystal structure of human methylmalonyl-CoA mutase in complex with adenosylcobalamin and malonyl-CoA

Summary for 2XIQ

Entry DOI	10.2210/pdb2xiq/pdb
Related	2XIJ
Descriptor	METHYLMALONYL-COA MUTASE, MITOCHONDRIAL, COBALAMIN, 5'-DEOXYADENOSINE, ... (5 entities in total)
Functional Keywords	organic aciduria, isomerase, metabolic disease, vitamin b12
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	2
Total formula weight	174542.00
Authors	Yue, W.W.,Froese, D.S.,Kochan, G.,Chaikuad, A.,Krojer, T.,Muniz, J.,Ugochukwu, E.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U. (deposition date: 2010-06-30, release date: 2010-09-29, Last modification date: 2023-12-20)
Primary citation	Froese, D.S.,Kochan, G.,Muniz, J.,Wu, X.,Gileadi, C.,Ugochukwu, E.,Krysztofinska, E.,Gravel, R.A.,Oppermann, U.,Yue, W.W. Structures of the Human Gtpase Mmaa and Vitamin B12-Dependent Methylmalonyl-Coa Mutase and Insight Into Their Complex Formation. J.Biol.Chem., 285:38204-, 2010 Cited by PubMed: 20876572 DOI: 10.1074/JBC.M110.177717 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation