2XG3

Human galectin-3 in complex with a benzamido-N-acetyllactoseamine inhibitor

Summary for 2XG3

Entry DOI	10.2210/pdb2xg3/pdb
Related	1A3K 1KJL 1KJR
Descriptor	Galectin-3, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	ige-binding protein, lectin, sugar binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	16214.95
Authors	Diehl, C.,Engstrom, O.,Delaine, T.,Hakansson, M.,Genheden, S.,Modig, K.,Leffler, H.,Ryde, U.,Nilsson, U.,Akke, M. (deposition date: 2010-05-30, release date: 2010-10-13, Last modification date: 2020-07-29)
Primary citation	Diehl, C.,Engstrom, O.,Delaine, T.,Hakansson, M.,Genheden, S.,Modig, K.,Leffler, H.,Ryde, U.,Nilsson, U.J.,Akke, M. Protein flexibility and conformational entropy in ligand design targeting the carbohydrate recognition domain of galectin-3. J. Am. Chem. Soc., 132:14577-14589, 2010 Cited by PubMed: 20873837 DOI: 10.1021/ja105852y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation