2XFO
tranylcypromine-inhibited human monoamine oxidase B Ile199Ala mutant in complex with 2-(2-benzofuranyl)-2-imidazoline
Summary for 2XFO
Entry DOI | 10.2210/pdb2xfo/pdb |
Related | 1GOS 1H8R 1OJ9 1OJA 1OJB 1OJC 1OJD 1S2Q 1S2Y 1S3B 1S3E 2BK3 2BK4 2BK5 2BYB 2C64 2C65 2C66 2C67 2C70 2C72 2C73 2C75 2C76 2V5Z 2V60 2V61 2VRL 2VRM 2VZ2 2XCG 2XFN 2XFP 2XFQ |
Descriptor | Amine oxidase [flavin-containing] B, [[(2R,3S,4S)-5-[(4AS)-7,8-DIMETHYL-2,4-DIOXO-4A,5-DIHYDROBENZO[G]PTERIDIN-10-YL]-2,3,4-TRIHYDROXY-PENTOXY]-HYDROXY-PHOSPHORYL] [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL HYDROGEN PHOSPHATE, 3-PHENYLPROPANAL, ... (6 entities in total) |
Functional Keywords | flavoprotein, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 119801.16 |
Authors | Bonivento, D.,Milczek, E.M.,McDonald, G.R.,Binda, C.,Holt, A.,Edmondson, D.E.,Mattevi, A. (deposition date: 2010-05-26, release date: 2010-10-06, Last modification date: 2023-12-20) |
Primary citation | Bonivento, D.,Milczek, E.M.,McDonald, G.R.,Binda, C.,Holt, A.,Edmondson, D.E.,Mattevi, A. Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285:36849-36856, 2010 Cited by PubMed: 20855894DOI: 10.1074/jbc.M110.169482 PDB entries with the same primary citation |
Experimental method |
Structure validation
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