2XFO
tranylcypromine-inhibited human monoamine oxidase B Ile199Ala mutant in complex with 2-(2-benzofuranyl)-2-imidazoline
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Amine oxidase [flavin-containing] B | polymer | 520 | 58795.7 | 2 | UniProt (P27338) Pfam (PF01593) In PDB | Homo sapiens (Human) | Monoamine oxidase type B,MAO-B |
| 2 | A | [[(2R,3S,4S)-5-[(4AS)-7,8-DIMETHYL-2,4-DIOXO-4A,5-DIHYDROBENZO[G]PTERIDIN-10-YL]-2,3,4-TRIHYDROXY-PENTOXY]-HYDROXY-PHOSPHORYL] [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL HYDROGEN PHOSPHATE | non-polymer | 787.6 | 1 | Chemie (FA8) | |||
| 3 | A, B | 3-PHENYLPROPANAL | non-polymer | 134.2 | 2 | Chemie (3PL) | |||
| 4 | A, B | 2-(2-BENZOFURANYL)-2-IMIDAZOLINE | non-polymer | 184.2 | 2 | Chemie (XCG) | |||
| 5 | B | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 6 | water | water | 18.0 | 303 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 520 (UniProt: P27338)
| PDB | External Database | Details |
|---|---|---|
| Ala 199 | Ile 199 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 117591.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2209.9 | |
| All* | Total formula weight | 119801.2 |
