2XB9

Structure of Helicobacter pylori type II dehydroquinase in complex with inhibitor compound (2R)-2-(4-methoxybenzyl)-3-dehydroquinic acid

Summary for 2XB9

Entry DOI	10.2210/pdb2xb9/pdb
Related	1J2Y 2C4V 2C4W 2C57 2WKS 2XB8
Descriptor	3-DEHYDROQUINATE DEHYDRATASE, (1R,2R,4S,5R)-1,4,5-TRIHYDROXY-2-(4-METHOXYBENZYL)-3-OXOCYCLOHEXANECARBOXYLIC ACID, CITRIC ACID, ... (4 entities in total)
Functional Keywords	lyase, amino acid biosynthesis
Biological source	HELICOBACTER PYLORI
Total number of polymer chains	3
Total formula weight	56310.46
Authors	Otero, J.M.,Tizon, L.,Llamas-Saiz, A.L.,Fox, G.C.,Gonzalez-Bello, C.,van Raaij, M.J. (deposition date: 2010-04-08, release date: 2010-09-15, Last modification date: 2023-12-20)
Primary citation	Peon, A.,Otero, J.M.,Tizon, L.,Prazeres, V.F.V.,Llamas-Saiz, A.L.,Fox, G.C.,van Raaij, M.J.,Lamb, H.,Hawkins, A.R.,Gago, F.,Castedo, L.,Gonzalez-Bello, C. Understanding the Key Factors that Control the Inhibition of Type II Dehydroquinase by (2R)-2- Benzyl-3-Dehydroquinic Acids. Chemmedchem, 5:1726-, 2010 Cited by PubMed: 20815012 DOI: 10.1002/CMDC.201000281 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.75 Å)

Structure validation