2X9F

ephB4 kinase domain inhibitor complex

Summary for 2X9F

Entry DOI	10.2210/pdb2x9f/pdb
Related	2BBA 2VWU 2VWV 2VWW 2VWX 2VWY 2VWZ 2VX0 2VX1
Descriptor	EPHRIN TYPE-B RECEPTOR 4, N^4^-1H-INDAZOL-4-YL-N^2^-[3-(METHYLSULFONYL)PHENYL]PYRIMIDINE-2,4-DIAMINE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	transferase, atp-binding, glycoprotein, transmembrane
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	34363.85
Authors	Read, J.,Brassington, C.A.,Green, I.,McCall, E.J.,Valentine, A.L.,Barratt, D. (deposition date: 2010-03-17, release date: 2010-09-29, Last modification date: 2023-12-20)
Primary citation	Bardelle, C.,Barlaam, B.,Brooks, N.,Coleman, T.,Cross, D.,Ducray, R.,Green, I.,Brempt, C.L.,Olivier, A.,Read, J. Inhibitors of the Tyrosine Kinase Ephb4. Part 3: Identification of Non-Benzodioxole-Based Kinase Inhibitors. Bioorg.Med.Chem.Lett., 20:6242-, 2010 Cited by PubMed: 20850301 DOI: 10.1016/J.BMCL.2010.08.100 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation