2X72

CRYSTAL STRUCTURE OF THE CONSTITUTIVELY ACTIVE E113Q,D2C,D282C RHODOPSIN MUTANT WITH BOUND GALPHACT PEPTIDE.

2X72 の概要

• エントリーDOI: 10.2210/pdb2x72/pdb
• 関連するPDBエントリー: 1AQG 1BOJ 1BOK 1EDS 1EDV 1EDW 1EDX 1F88 1FDF 1FQJ 1FQK 1GZM 1HZX 1JFP 1L9H 1LN6 1LVZ 1N3M 1NZS 1OV0 1OV1 1TAD 1TAG 1TND 1U19 1VQX 2I35 2I36 2I37 2J4Y
• 分子名称: RHODOPSIN, GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: signaling protein, chromophore, lipoprotein, glycoprotein, transmembrane, retinal protein, g-protein coupled receptor, sensory transduction, photoreceptor protein
• 由来する生物種: BOS TAURUS (CATTLE); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43699.47

構造登録者

Standfuss, J.,Edwards, P.C.,Dantona, A.,Fransen, M.,Xie, G.,Oprian, D.D.,Schertler, G.F.X. (登録日: 2010-02-22, 公開日: 2011-03-16, 最終更新日: 2023-12-20)

• 主引用文献: Standfuss, J.,Edwards, P.C.,Dantona, A.,Fransen, M.,Xie, G.,Oprian, D.D.,Schertler, G.F.X.; The Structural Basis of Agonist Induced Activation in Constitutively Active Rhodopsin; Nature, 471:656-, 2011; PubMed: 21389983; DOI: 10.1038/NATURE09795

実験手法

X-RAY DIFFRACTION (3 Å)