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2X5W

X-ray structure of Mycobacterium tuberculosis cytochrome P450 CYP125 in complex with substrate cholest-4-en-3-one

Summary for 2X5W
Entry DOI10.2210/pdb2x5w/pdb
Related2X5L
DescriptorPUTATIVE CYTOCHROME P450 125, SULFATE ION, (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE, ... (6 entities in total)
Functional Keywordscholesterol degradation, metal-binding, oxidoreductase
Biological sourceMYCOBACTERIUM TUBERCULOSIS
Total number of polymer chains1
Total formula weight50610.82
Authors
Ouellet, H.,Guan, S.,Johnston, J.B.,Chow, E.D.,Kells, P.M.,Burlingame, A.L.,Cox, J.S.,Podust, L.M.,Ortiz de Montellano, P.R. (deposition date: 2010-02-10, release date: 2010-06-16, Last modification date: 2023-12-20)
Primary citationOuellet, H.,Guan, S.,Johnston, J.B.,Chow, E.D.,Kells, P.M.,Burlingame, A.L.,Cox, J.S.,Podust, L.M.,Ortiz de Montellano, P.R.
Mycobacterium Tuberculosis Cyp125A1, a Steroid C27 Monooxygenase that Detoxifies Intracellularly Generated Cholest-4-En-3-One.
Mol.Microbiol., 77:730-, 2010
Cited by
PubMed: 20545858
DOI: 10.1111/J.1365-2958.2010.07243.X
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.58 Å)
Structure validation

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