2X0Y

Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds

Summary for 2X0Y

Entry DOI	10.2210/pdb2x0y/pdb
Related	2CBI 2CBJ 2J62 2JH2 2V5C 2V5D 2VUR 2WB5
Descriptor	O-GLCNACASE NAGJ, 7-[(2S)-2,3-DIHYDROXYPROPYL]-1,3-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE (3 entities in total)
Functional Keywords	glycosidase, hydrolase, cell adhesion
Biological source	CLOSTRIDIUM PERFRINGENS
Total number of polymer chains	2
Total formula weight	133885.91
Authors	Dorfmueller, H.C.,van Aalten, D.M.F. (deposition date: 2009-12-18, release date: 2010-01-12, Last modification date: 2023-12-20)
Primary citation	Dorfmueller, H.C.,Van Aalten, D.M.F. Screening-Based Discovery of Drug-Like O-Glcnacase Inhibitor Scaffolds FEBS Lett., 584:694-, 2010 Cited by PubMed: 20026047 DOI: 10.1016/J.FEBSLET.2009.12.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation