2WVT

Crystal structure of an alpha-L-fucosidase GH29 from Bacteroides thetaiotaomicron in complex with a novel iminosugar fucosidase inhibitor

Summary for 2WVT

Entry DOI	10.2210/pdb2wvt/pdb
Related	2WVS 2WVU 2WVV
Descriptor	ALPHA-L-FUCOSIDASE, (2S,3R,5R,6S)-3,4,5-TRIHYDROXY-2,6-BIS(HYDROXYMETHYL)PIPERIDINIUM, GLYCEROL, ... (5 entities in total)
Functional Keywords	hydrolase, alpha-l-fucose, glycoside hydrolase family 29
Biological source	BACTEROIDES THETAIOTAOMICRON
Total number of polymer chains	2
Total formula weight	103787.46
Authors	Lammerts van Bueren, A.,Ardevol, A.,Fayers-Kerr, J.,Luo, B.,Zhang, Y.,Sollogoub, M.,Bleriot, Y.,Rovira, C.,Davies, G.J. (deposition date: 2009-10-20, release date: 2010-02-02, Last modification date: 2023-12-20)
Primary citation	Lammerts Van Bueren, A.,Ardevol, A.,Fayers-Kerr, J.,Luo, B.,Zhang, Y.,Sollogoub, M.,Bleriot, Y.,Rovira, C.,Davies, G.J. Analysis of the Reaction Coordinate of Alpha-L-Fucosidases: A Combined Structural and Quantum Mechanical Approach. J.Am.Chem.Soc., 132:1804-, 2010 Cited by PubMed: 20092273 DOI: 10.1021/JA908908Q PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation