2WSL
Aged Form of Human Butyrylcholinesterase Inhibited by Tabun Analogue TA4
Summary for 2WSL
Entry DOI | 10.2210/pdb2wsl/pdb |
Related | 1EHO 1EHQ 1KCJ 1P0I 1P0M 1P0P 1P0Q 1XLU 1XLV 1XLW 2J4C 2WID 2WIF 2WIG 2WIJ 2WIK 2WIL |
Descriptor | CHOLINESTERASE, FLUORIDE ION, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | tabun, aging, hydrolase, inhibition, butyrylcholinesterase, glycoprotein, serine esterase, disease mutation |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 62217.18 |
Authors | Carletti, E.,Aurbek, N.,Gillon, E.,Loiodice, M.,Nicolet, Y.,Fontecilla, J.,Masson, P.,Thiermann, H.,Nachon, F.,Worek, F. (deposition date: 2009-09-08, release date: 2009-09-15, Last modification date: 2023-12-20) |
Primary citation | Carletti, E.,Aurbek, N.,Gillon, E.,Loiodice, M.,Nicolet, Y.,Fontecilla-Camps, J.C.,Masson, P.,Thiermann, H.,Nachon, F.,Worek, F. Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun. Biochem. J., 421:97-106, 2009 Cited by PubMed: 19368529DOI: 10.1042/BJ20090091 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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