2WPK

factor IXa superactive triple mutant, ethylene glycol-soaked

Summary for 2WPK

Related1EDM 1CFH 2WPM 1MGX 1CFI 2WPI 2WPL 2WPH 2WPJ 1IXA 1RFN 1NL0
Related PRD IDPRD_001148
DescriptorCOAGULATION FACTOR IXA LIGHT CHAIN, D-PHE-PRO-ARG-CHLOROMETHYL KETONE, COAGULATION FACTOR IXA HEAVY CHAIN, ... (6 entities in total)
Functional Keywordsblood clotting, hydrolase, hemostasis, hemophilia
Biological sourceHOMO SAPIENS (HUMAN)
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Cellular locationSecreted  P00740 P00740
Total number of polymer chains3
Total molecular weight33102.71
Authors
Zogg, T.,Brandstetter, H. (deposition date: 2009-08-06, release date: 2009-12-22, Last modification date: 2017-07-05)
Primary citation
Zogg, T.,Brandstetter, H.
Structural Basis of the Cofactor- and Substrate-Assisted Activation of Human Coagulation Factor Ixa
Structure, 17:1669-, 2009
PubMed: 20004170 (PDB entries with the same primary citation)
DOI: 10.1016/J.STR.2009.10.011
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.21 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.260131.0%2.8%4.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution