2WL5

BIOSYNTHETIC THIOLASE FROM Z. RAMIGERA. COMPLEX OF THE H348N MUTANT WITH COENZYME A.

Summary for 2WL5

• Entry DOI: 10.2210/pdb2wl5/pdb
• Related: 1DLU 1DLV 1DM3 1M1O 1M1T 1M3K 1M3Z 1M4S 1M4T 1NL7 1OU6 1QFL 2VTZ 2VU0 2VU1 2VU2 2WKT 2WKU 2WKV 2WL4 2WL6
• Descriptor: ACETYL-COA ACETYLTRANSFERASE, SULFATE ION, D-mannose, ... (8 entities in total)
• Functional Keywords: acyltransferase, cytoplasm, phb biosynthesis, thiolase fold, transferase
• Biological source: ZOOGLOEA RAMIGERA; More
• Cellular location: Cytoplasm: P07097 P07097
• Total number of polymer chains: 4
• Total formula weight: 165759.68

Authors

Merilainen, G.,Poikela, V.,Kursula, P.,Wierenga, R.K. (deposition date: 2009-06-22, release date: 2009-11-03, Last modification date: 2023-12-13)

• Primary citation: Merilainen, G.,Poikela, V.,Kursula, P.,Wierenga, R.K.; The Thiolase Reaction Mechanism: The Importance of Asn316 and His348 for Stabilizing the Enolate Intermediate of the Claisen Condensation.; Biochemistry, 48:11011-, 2009; PubMed: 19842716; DOI: 10.1021/BI901069H

Experimental method

X-RAY DIFFRACTION (1.8 Å)