2WKH

Crystal structure of the acyl-enzyme OXA-10 K70C-Ampicillin at pH 7

Summary for 2WKH

Entry DOI	10.2210/pdb2wkh/pdb
Related	1E3U 1E4D 1EWZ 1FOF 1K4E 1K4F 1K54 1K55 1K56 1K57 1K6R 1K6S 2WGI 2WGV 2WGW 2WKI
Descriptor	BETA-LACTAMASE OXA-10, (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, SULFATE ION, ... (4 entities in total)
Functional Keywords	hydrolase, antibiotic resistance, class d beta-lactamase, plasmid encoded
Biological source	PSEUDOMONAS AERUGINOSA
Total number of polymer chains	2
Total formula weight	56588.16
Authors	Vercheval, L.,Bauvois, C.,Kerff, F.,Sauvage, E.,Guiet, R.,Charlier, P.,Galleni, M. (deposition date: 2009-06-11, release date: 2010-08-25, Last modification date: 2023-12-13)
Primary citation	Vercheval, L.,Bauvois, C.,Di Paolo, A.,Borel, F.,Ferrer, J.,Sauvage, E.,Matagne, A.,Frere, J.,Charlier, P.,Galleni, M.,Kerff, F. Three Factors that Modulate the Activity of Class D Beta-Lactamases and Interfere with the Post-Translational Carboxylation of Lys70. Biochem.J., 432:495-, 2010 Cited by PubMed: 21108605 DOI: 10.1042/BJ20101122 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.791 Å)

Structure validation