2WG3
Crystal structure of the complex between human hedgehog-interacting protein HIP and desert hedgehog without calcium
Summary for 2WG3
Entry DOI | 10.2210/pdb2wg3/pdb |
Related | 2WFQ 2WFR 2WFT 2WFX 2WG4 |
Descriptor | DESERT HEDGEHOG PROTEIN N-PRODUCT, HEDGEHOG-INTERACTING PROTEIN, ZINC ION, ... (7 entities in total) |
Functional Keywords | lipoprotein, development, membrane, secreted, protease, palmitate, hydrolase, developmental protein, autocatalytic cleavage, signal transduction, egf-like domain, disease mutation, hedgehog signaling, glycoprotein, cell membrane, disulfide bond, signaling protein |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 4 |
Total formula weight | 141903.02 |
Authors | Bishop, B.,Aricescu, A.R.,Harlos, K.,O'Callaghan, C.A.,Jones, E.Y.,Siebold, C. (deposition date: 2009-04-15, release date: 2009-06-30, Last modification date: 2023-12-13) |
Primary citation | Bishop, B.,Aricescu, A.R.,Harlos, K.,O'Callaghan, C.A.,Jones, E.Y.,Siebold, C. Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol., 16:698-, 2009 Cited by PubMed: 19561611DOI: 10.1038/NSMB.1607 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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