2W9T
Staphylococcus aureus S1:DHFR
Summary for 2W9T
Entry DOI | 10.2210/pdb2w9t/pdb |
Related | 2W9S |
Descriptor | DIHYDROFOLATE REDUCTASE TYPE 1 (2 entities in total) |
Functional Keywords | antibiotic resistance, staphylococcus aureus, dhfr, nadp, plasmid, trimethoprim, oxidoreductase, trimethoprim resistance, one-carbon metabolism, methotrexate resistance |
Biological source | STAPHYLOCOCCUS AUREUS |
Total number of polymer chains | 2 |
Total formula weight | 37001.98 |
Authors | Soutter, H.H.,Miller, J.R. (deposition date: 2009-01-28, release date: 2009-03-24, Last modification date: 2024-05-08) |
Primary citation | Heaslet, H.,Harris, M.,Fahnoe, K.,Sarver, R.,Putz, H.,Chang, J.,Subramanyam, C.,Barreiro, G.,Miller, J.R. Structural Comparison of Chromosomal and Exogenous Dihydrofolate Reductase from Staphylococcus Aureus in Complex with the Potent Inhibitor Trimethoprim. Proteins, 76:706-, 2009 Cited by PubMed: 19280600DOI: 10.1002/PROT.22383 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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