2W4Q

Crystal structure of human zinc-binding alcohol dehydrogenase 1 (ZADH1) in ternary complex with NADP and 18beta-glycyrrhetinic acid

2W4Q の概要

• エントリーDOI: 10.2210/pdb2w4q/pdb
• 分子名称: PROSTAGLANDIN REDUCTASE 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (3BETA,5BETA,14BETA)-3-HYDROXY-11-OXOOLEAN-12-EN-29-OIC ACID, ... (5 entities in total)
• 機能のキーワード: 15-oxoprostalglandin, medium-chain dehydrogenase/reductase, nadp, oxidoreductase
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 41400.73

構造登録者

Shafqat, N.,Yue, W.W.,Ugochukwu, E.,Picaud, S.,Niesen, F.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U. (登録日: 2008-11-30, 公開日: 2009-01-20, 最終更新日: 2023-12-13)

• 主引用文献: Shafqat, N.,Yue, W.W.,Niesen, F.,Oppermann, U.; Crystal Structure of Human Zinc-Binding Alcohol Dehydrogenase 1; To be Published,

実験手法

X-RAY DIFFRACTION (2 Å)