2W3Q

Structure and inhibition of the CO2-sensing carbonic anhydrase Can2 from the pathogenic fungus Cryptococcus neoformans

Summary for 2W3Q

Entry DOI	10.2210/pdb2w3q/pdb
Related	2W3N
Descriptor	CARBONIC ANHYDRASE 2, ZINC ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	beta-class carbonic anhydrase, lyase, inhibition, sulfonamide, cryptococcus neoformans
Biological source	CRYPTOCOCCUS NEOFORMANS
Total number of polymer chains	1
Total formula weight	27086.45
Authors	Schlicker, C.,Hall, R.A.,Vullo, D.,Middelhaufe, S.,Gertz, M.,Supuran, C.T.,Muehlschlegel, F.A.,Steegborn, C. (deposition date: 2008-11-14, release date: 2008-12-30, Last modification date: 2023-12-13)
Primary citation	Schlicker, C.,Hall, R.A.,Vullo, D.,Middelhaufe, S.,Gertz, M.,Supuran, C.T.,Muehlschlegel, F.A.,Steegborn, C. Structure and Inhibition of the Co(2)-Sensing Carbonic Anhydrase Can2 from the Pathogenic Fungus Cryptococcus Neoformans. J.Mol.Biol., 385:1207-, 2009 Cited by PubMed: 19071134 DOI: 10.1016/J.JMB.2008.11.037 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.34 Å)

Structure validation