2W22
Activation Mechanism of Bacterial Thermoalkalophilic Lipases
Summary for 2W22
Entry DOI | 10.2210/pdb2w22/pdb |
Descriptor | TRIACYLGLYCEROL LIPASE, CALCIUM ION, ZINC ION, ... (6 entities in total) |
Functional Keywords | thermoalkalophilic lipases, hydrolase, open conformation, activation mechanism |
Biological source | GEOBACILLUS THERMOCATENULATUS |
Total number of polymer chains | 1 |
Total formula weight | 45034.00 |
Authors | Carrasco-Lopez, C.,Godoy, C.,De Las Rivas, B.,Fernandez-Lorente, G.,Palomo, J.M.,Guisan, J.M.,Fernandez-Lafuente, R.,Hermoso, J.A. (deposition date: 2008-10-23, release date: 2008-12-16, Last modification date: 2023-12-13) |
Primary citation | Carrasco-Lopez, C.,Godoy, C.,de Las Rivas, B.,Fernandez-Lorente, G.,Palomo, J.M.,Guisan, J.M.,Fernandez-Lafuente, R.,Martinez-Ripoll, M.,Hermoso, J.A. Activation of bacterial thermoalkalophilic lipases is spurred by dramatic structural rearrangements. J. Biol. Chem., 284:4365-4372, 2009 Cited by PubMed: 19056729DOI: 10.1074/jbc.M808268200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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