2W19

Non-covalent complex between dahp synthase and chorismate mutase from Mycobacterium tuberculosis

Summary for 2W19

Entry DOI	10.2210/pdb2w19/pdb
Related	2B7O 2VKL 2W1A
Descriptor	3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE AROG, CHORISMATE MUTASE, GLYCEROL, ... (5 entities in total)
Functional Keywords	transferase-isomerase complex, transferase isomerase complex, aromatic amino acid biosynthesis, multi-enzyme complex, protein-protein interactions, enzyme activation, feedback regulation, shikimate pathway, complex formation, mycobacterium tuberculosis rv0948c, isomerase, transferase, drug target, enzyme catalysis, transferase/isomerase
Biological source	MYCOBACTERIUM TUBERCULOSIS More
Total number of polymer chains	4
Total formula weight	125299.94
Authors	Okvist, M.,Sasso, S.,Roderer, K.,Gamper, M.,Codoni, G.,Krengel, U.,Kast, P. (deposition date: 2008-10-16, release date: 2009-07-07, Last modification date: 2023-12-13)
Primary citation	Sasso, S.,Okvist, M.,Roderer, K.,Gamper, M.,Codoni, G.,Krengel, U.,Kast, P. Structure and Function of a Complex between Chorismate Mutase and Dahp Synthase: Efficiency Boost for the Junior Partner. Embo J., 28:2128-, 2009 Cited by PubMed: 19556970 DOI: 10.1038/EMBOJ.2009.165 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation