2VWI

Structure of the OSR1 kinase, a hypertension drug target

Summary for 2VWI

• Entry DOI: 10.2210/pdb2vwi/pdb
• Related: 2V3S
• Descriptor: SERINE/THREONINE-PROTEIN KINASE OSR1, GOLD ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
• Functional Keywords: kinase, ste kinase, hypertension, transferase
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasm: O95747
• Total number of polymer chains: 4
• Total formula weight: 140253.68

Authors

Villa, F.,Deak, M.,Alessi, D.R.,vanAalten, D.M.F. (deposition date: 2008-06-25, release date: 2008-07-08, Last modification date: 2013-04-17)

• Primary citation: Villa, F.,Deak, M.,Alessi, D.R.,Van Aalten, D.M.F.; Structure of the Osr1 Kinase, a Hypertension Drug Target.; Proteins, 73:1082-, 2008; PubMed: 18831043; DOI: 10.1002/PROT.22238

Experimental method

X-RAY DIFFRACTION (2.15 Å)