2VSZ
Crystal Structure of the ELMO1 PH domain
Summary for 2VSZ
Entry DOI | 10.2210/pdb2vsz/pdb |
Descriptor | ENGULFMENT AND CELL MOTILITY PROTEIN 1 (2 entities in total) |
Functional Keywords | apoptosis, rac signalling, sh3-binding, phagocytosis, elmo, dock180, phosphoinositide binding, guanine nucleotide exchange factor |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: Q92556 |
Total number of polymer chains | 2 |
Total formula weight | 34205.50 |
Authors | Komander, D.,Patel, M.,Barford, D.,Cote, J.-F. (deposition date: 2008-05-01, release date: 2009-03-10, Last modification date: 2024-05-08) |
Primary citation | Komander, D.,Patel, M.,Laurin, M.,Fradet, N.,Pelletier, A.,Barford, D.,Cote, J.-F. An Alpha-Helical Extension of the Elmo1 Pleckstrin Homology Domain Mediates Direct Interaction to Dock180 and is Critical in Rac Signaling. Molecular Biology of the Cell, 19:4837-, 2008 Cited by PubMed: 18768751DOI: 10.1091/MBC.E08-04-0345 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report