2VQ3

Crystal Structure of the Membrane Proximal Oxidoreductase Domain of Human Steap3, the Dominant Ferric Reductase of the Erythroid Transferrin Cycle

Summary for 2VQ3

Entry DOI	10.2210/pdb2vq3/pdb
Related	2VNS
Descriptor	METALLOREDUCTASE STEAP3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CITRIC ACID, ... (4 entities in total)
Functional Keywords	metal-binding, transmembrane, rossmann fold, transport, cell cycle, transferrin, flavoprotein, alternative splicing, transferrin receptor, ferrireductase, ferric-reductase, iron transport, phosphoprotein, oxidoreductase, steap3, copper, membrane, endosome, apoptosis, tf, nad, tfr, fad, fno, nadp, tfr1, iron, steap, polymorphism, glycoprotein, ion transport, dinucleotide-binding domain
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Endosome membrane; Multi-pass membrane protein (By similarity): Q658P3
Total number of polymer chains	2
Total formula weight	48310.29
Authors	Sendamarai, A.K.,Ohgami, R.S.,Fleming, M.D.,Lawrence, C.M. (deposition date: 2008-03-10, release date: 2008-05-06, Last modification date: 2024-01-31)
Primary citation	Sendamarai, A.K.,Ohgami, R.S.,Fleming, M.D.,Lawrence, C.M. Structure of the Membrane Proximal Oxidoreductase Domain of Human Steap3, the Dominant Ferrireductase of the Erythroid Transferrin Cycle Proc.Natl.Acad.Sci.USA, 105:7410-, 2008 Cited by PubMed: 18495927 DOI: 10.1073/PNAS.0801318105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation