2VQ3
Crystal Structure of the Membrane Proximal Oxidoreductase Domain of Human Steap3, the Dominant Ferric Reductase of the Erythroid Transferrin Cycle
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE NAP A1210 |
| Chain | Residue |
| A | SER36 |
| A | HIS95 |
| A | SER98 |
| A | VAL114 |
| A | SER115 |
| A | ASN116 |
| A | ASN147 |
| A | ILE149 |
| A | SER150 |
| A | ALA151 |
| A | HOH416 |
| A | GLY37 |
| A | HOH436 |
| A | HOH410 |
| A | HOH444 |
| A | HOH401 |
| A | HOH402 |
| A | ASP38 |
| A | PHE39 |
| A | SER58 |
| A | ARG59 |
| A | ALA90 |
| A | VAL91 |
| A | PHE92 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE NAP B1210 |
| Chain | Residue |
| B | GLY35 |
| B | SER36 |
| B | GLY37 |
| B | ASP38 |
| B | PHE39 |
| B | SER58 |
| B | ARG59 |
| B | ALA90 |
| B | VAL91 |
| B | PHE92 |
| B | HIS95 |
| B | SER98 |
| B | VAL114 |
| B | SER115 |
| B | ASN116 |
| B | ILE149 |
| B | ALA151 |
| B | HOH402 |
| B | HOH422 |
| B | HOH401 |
| B | HOH429 |
| B | HOH403 |
| B | HOH451 |
| B | HOH443 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CIT A1211 |
| Chain | Residue |
| B | LYS62 |
| B | ARG66 |
| A | HOH427 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 412 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | MET1-ARG207 | |
| B | MET1-ARG207 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:18495927, ECO:0007744|PDB:2VQ3 |
| Chain | Residue | Details |
| A | SER36 | |
| A | SER58 | |
| A | VAL91 | |
| B | SER36 | |
| B | SER58 | |
| B | VAL91 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:18495927 |
| Chain | Residue | Details |
| A | ASN116 | |
| A | ALA151 | |
| B | ASN116 | |
| B | ALA151 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q687X5 |
| Chain | Residue | Details |
| A | TRP152 | |
| A | ASP160 | |
| B | TRP152 | |
| B | ASP160 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER11 | |
| A | SER17 | |
| A | SER20 | |
| B | SER11 | |
| B | SER17 | |
| B | SER20 |
