2VL4
Structural and biochemical evidence for a boat-like transition state in beta-mannosidases
Summary for 2VL4
Entry DOI | 10.2210/pdb2vl4/pdb |
Related | 2JE8 2VJX 2VMF 2VO5 2VOT 2VQT 2VQU |
Descriptor | BETA-MANNOSIDASE, (2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-HYDROXYMETHYL-PIPERIDINE, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | linear free energy relationship, hydrolase, transition state mimic, mannosidase, glycoside hydrolase |
Biological source | BACTEROIDES THETAIOTAOMICRON |
Total number of polymer chains | 2 |
Total formula weight | 199596.46 |
Authors | Tailford, L.E.,Offen, W.A.,Smith, N.L.,Dumon, C.,Moreland, C.,Gratien, J.,Heck, M.P.,Stick, R.V.,Bleriot, Y.,Vasella, A.,Gilbert, H.J.,Davies, G.J. (deposition date: 2008-01-08, release date: 2008-04-01, Last modification date: 2023-12-13) |
Primary citation | Tailford, L.E.,Offen, W.A.,Smith, N.L.,Dumon, C.,Morland, C.,Gratien, J.,Heck, M.P.,Stick, R.V.,Bleriot, Y.,Vasella, A.,Gilbert, H.J.,Davies, G.J. Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases. Nat.Chem.Biol., 4:306-, 2008 Cited by PubMed: 18408714DOI: 10.1038/NCHEMBIO.81 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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