2VKZ

Structure of the cerulenin-inhibited fungal fatty acid synthase type I multienzyme complex

2VKZ の概要

• エントリーDOI: 10.2210/pdb2vkz/pdb
• 関連するPDBエントリー: 2UV8
• 分子名称: FATTY ACID SYNTHASE SUBUNIT ALPHA, FATTY ACID SYNTHASE SUBUNIT BETA, (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, ... (4 entities in total)
• 機能のキーワード: transferase, phosphorylation, phosphopantetheine, fatty acid synthase, multifunctional enzyme, oxidoreductase, lipid synthesis, fas, nad, nadp, lyase, cerulenin, hydrolase, fatty acid biosynthesis
• 由来する生物種: SACCHAROMYCES CEREVISIAE (BAKER'S YEAST); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 1310419.27

構造登録者

Johansson, P.,Wiltschi, B.,Kumari, P.,Kessler, B.,Vonrhein, C.,Vonck, J.,Oesterhelt, D.,Grininger, M. (登録日: 2008-01-07, 公開日: 2008-08-12, 最終更新日: 2017-06-21)

• 主引用文献: Johansson, P.,Wiltschi, B.,Kumari, P.,Kessler, B.,Vonrhein, C.,Vonck, J.,Oesterhelt, D.,Grininger, M.; Inhibition of the Fungal Fatty Acid Synthase Type I Multienzyme Complex.; Proc.Natl.Acad.Sci.USA, 105:12803-, 2008; PubMed: 18725634; DOI: 10.1073/PNAS.0805827105

実験手法

X-RAY DIFFRACTION (4 Å)