2VJ0
Crystal structure of the alpha-adaptin appendage domain, from the AP2 adaptor complex, in complex with an FXDNF peptide from amphiphysin1 and a WVXF peptide from synaptojanin P170
Summary for 2VJ0
Entry DOI | 10.2210/pdb2vj0/pdb |
Related | 1B9K 1GW5 1KY6 1KY7 1KYF 1KYU 1QTP 1QTS 1W80 2DNR |
Descriptor | AP-2 COMPLEX SUBUNIT ALPHA-2, SYNAPTOJANIN-1, AMPHIPHYSIN, ... (8 entities in total) |
Functional Keywords | protein transport, cytoplasmic vesicle, alternative splicing, transport, coated pit, sh3 domain, endocytosis, alpha-adaptin, golgi apparatus, phosphorylation, ap2, synapse, membrane, cytoplasm, coiled coil, amphiphysin, cytoskeleton, synaptojanin, lipid-binding, cell junction |
Biological source | MUS MUSCULUS (MOUSE) More |
Cellular location | Cell membrane: P17427 Cytoplasm (By similarity): O43426 Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity): O08838 |
Total number of polymer chains | 3 |
Total formula weight | 30976.45 |
Authors | Ford, M.G.J.,Praefcke, G.J.K.,McMahon, H.T. (deposition date: 2007-12-06, release date: 2007-12-25, Last modification date: 2023-12-13) |
Primary citation | Olesen, L.E.,Ford, M.G.J.,Schmid, E.M.,Vallis, Y.,Madan Babu, M.,Li, P.H.,Mills, I.G.,Mcmahon, H.T.,Praefcke, G.J.K. Solitary and Repetitive Binding Motifs for the Ap2 Complex {Alpha}-Appendage in Amphiphysin and Other Accessory Proteins. J.Biol.Chem., 283:5099-, 2008 Cited by PubMed: 17986441DOI: 10.1074/JBC.M708621200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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