2VFE
Crystal structure of F96S mutant of Plasmodium falciparum triosephosphate isomerase with 3- phosphoglycerate bound at the dimer interface
Summary for 2VFE
Entry DOI | 10.2210/pdb2vfe/pdb |
Related | 1LYX 1LZO 1M7O 1M7P 1O5X 1VGA 1WOA 1WOB 1YDV 2VFD 2VFF 2VFG 2VFH 2VFI |
Descriptor | TRIOSEPHOSPHATE ISOMERASE, 3-PHOSPHOGLYCERIC ACID, GLYCEROL, ... (4 entities in total) |
Functional Keywords | 3-phosphoglycerate, plasmodium falciparum, isomerase, glycolysis, pentose shunt, gluconeogenesis, lipid synthesis, dimer interface, fatty acid biosynthesis, triosephosphate isomerase |
Biological source | PLASMODIUM FALCIPARUM (MALARIAL PARASITE) |
Total number of polymer chains | 2 |
Total formula weight | 56431.58 |
Authors | Gayathri, P.,Banerjee, M.,Vijayalakshmi, A.,Balaram, H.,Balaram, P.,Murthy, M.R.N. (deposition date: 2007-11-03, release date: 2008-12-09, Last modification date: 2023-12-13) |
Primary citation | Gayathri, P.,Banerjee, M.,Vijayalakshmi, A.,Balaram, H.,Balaram, P.,Murthy, M.R.N. Biochemical and Structural Characterization of Residue 96 Mutants of Plasmodium Falciparum Triosephosphate Isomerase: Active-Site Loop Conformation, Hydration and Identification of a Dimer-Interface Ligand-Binding Site. Acta Crystallogr.,Sect.D, 65:847-, 2009 Cited by PubMed: 19622869DOI: 10.1107/S0907444909018666 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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