2VFE
Crystal structure of F96S mutant of Plasmodium falciparum triosephosphate isomerase with 3- phosphoglycerate bound at the dimer interface
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | TRIOSEPHOSPHATE ISOMERASE | polymer | 248 | 27937.6 | 2 | UniProt (Q07412) Pfam (PF00121) | PLASMODIUM FALCIPARUM (MALARIAL PARASITE) | TIM, TRIOSE-PHOSPHATE ISOMERASE |
| 2 | C, E (A, B) | 3-PHOSPHOGLYCERIC ACID | non-polymer | 186.1 | 2 | Chemie (3PG) | |||
| 3 | D, F (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 264 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 248 (UniProt: Q07412)
| PDB | External Database | Details |
|---|---|---|
| Ser 96 | Phe 96 | engineered mutation |
| Val 163 | Ala 163 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55875.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 556.3 | |
| All* | Total formula weight | 56431.6 |
