2VES
Crystal Structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB-78485 inhibitor
Summary for 2VES
Entry DOI | 10.2210/pdb2ves/pdb |
Descriptor | UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION, (2R)-N-hydroxy-3-naphthalen-2-yl-2-[(naphthalen-2-ylsulfonyl)amino]propanamide, ... (5 entities in total) |
Functional Keywords | lpxc, hydrolase, bb-78485, antibiotics, deacetylase, lipid synthesis, metalloprotease, hydroxamic acid, gram-negative bacteria, lipopolysaccharide, lipid a biosynthesis |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 3 |
Total formula weight | 101351.28 |
Authors | Mochalkin, I.,Knafels, J.D. (deposition date: 2007-10-26, release date: 2008-01-15, Last modification date: 2023-12-13) |
Primary citation | Mochalkin, I.,Knafels, J.D.,Lightle, S. Crystal structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB-78485 inhibitor. Protein Sci., 17:450-457, 2008 Cited by PubMed: 18287278DOI: 10.1110/ps.073324108 PDB entries with the same primary citation |
Experimental method |
Structure validation
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