2VES
Crystal Structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB-78485 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | UDP-3-O-acyl-N-acetylglucosamine deacetylase | polymer | 299 | 33146.6 | 3 | UniProt (P47205) Pfam (PF03331) | Pseudomonas aeruginosa | UDP-3-O-acyl-GlcNAc deacetylase,UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase |
| 2 | D, F, G, I, K... (A, B, C) | ZINC ION | non-polymer | 65.4 | 7 | Chemie (ZN) | |||
| 3 | E, H, L (A, B, C) | (2R)-N-hydroxy-3-naphthalen-2-yl-2-[(naphthalen-2-ylsulfonyl)amino]propanamide | non-polymer | 420.5 | 3 | Chemie (GVR) | |||
| 4 | J, O (B, C) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | P, Q, R (A, B, C) | water | water | 18.0 | 1223 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 299 (UniProt: P47205)
| PDB | External Database | Details |
|---|---|---|
| Ser 40 | Cys 40 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 99439.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1911.4 | |
| All* | Total formula weight | 101351.3 |
