2VDE

Crystal Structure of the Open State of TolC Outer Membrane Component of Mutlidrug Efflux Pumps

Summary for 2VDE

Entry DOI	10.2210/pdb2vde/pdb
Related	1EK9 1TQQ 1TTQ 2VDD
Descriptor	OUTER MEMBRANE PROTEIN TOLC, CHLORIDE ION (2 entities in total)
Functional Keywords	outer membrane, alpha helical barrel, transport protein, multidrug efflux pump, integral membrane protein, membrane, transport, beta barrel, transmembrane
Biological source	ESCHERICHIA COLI
Total number of polymer chains	3
Total formula weight	152010.81
Authors	Bavro, V.N.,Pietras, Z.,Furnham, N.,Perez-Cano, L.,Fernandez-Recio, J.,Pei, X.Y.,Truer, R.,Misra, R.,Luisi, B. (deposition date: 2007-10-04, release date: 2008-04-22, Last modification date: 2023-12-13)
Primary citation	Bavro, V.N.,Pietras, Z.,Furnham, N.,Perez-Cano, L.,Fernandez-Recio, J.,Pei, X.Y.,Truer, R.,Misra, R.,Luisi, B. Assembly and Channel Opening in a Bacterial Drug Efflux Machine. Mol.Cell, 30:114-, 2008 Cited by PubMed: 18406332 DOI: 10.1016/J.MOLCEL.2008.02.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation