2VBJ
Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers
Summary for 2VBJ
Entry DOI | 10.2210/pdb2vbj/pdb |
Related | 1AF5 1BP7 1G9Y 1G9Z 1MOW 1N3E 1N3F 1T9I 1T9J 1U0C 1U0D 2VBL 2VBN 2VBO |
Descriptor | DNA ENDONUCLEASE I-CREI, 5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP*AP*GP*GP*AP*TP*CP*CP*TP*AP*A)-3', 5'-D(*TP*TP*AP*GP*GP*AP*TP*CP*CP*TP *TP*CP*AP*AP*AP*AP*AP*AP*GP*GP*CP*AP*GP*A)-3', ... (6 entities in total) |
Functional Keywords | double strand break (dsb), cutting dna endonucleases, amel3-4-calcium, uv-induced dna damage, homing endonucleases (hes), hydrolase-dna complex, hydrolase/dna |
Biological source | CHLAMYDOMONAS REINHARDTII More |
Total number of polymer chains | 4 |
Total formula weight | 49836.98 |
Authors | Redondo, P.,Prieto, J.,Munoz, I.G.,Alibes, A.,Stricher, F.,Serrano, L.,Arnould, S.,Perez, C.,Cabaniols, J.P.,Duchateau, P.,Paques, F.,Blanco, F.J.,Montoya, G. (deposition date: 2007-09-14, release date: 2008-10-28, Last modification date: 2023-12-13) |
Primary citation | Redondo, P.,Prieto, J.,Munoz, I.G.,Alibes, A.,Stricher, F.,Serrano, L.,Cabaniols, J.P.,Daboussi, F.,Arnould, S.,Perez, C.,Duchateau, P.,Paques, F.,Blanco, F.J.,Montoya, G. Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases Nature, 456:107-, 2008 Cited by PubMed: 18987743DOI: 10.1038/NATURE07343 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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