2VAX

Crystal structure of deacetylcephalosporin C acetyltransferase (Cephalosporin C-soak)

Summary for 2VAX

Entry DOI	10.2210/pdb2vax/pdb
Related	2VAT 2VAV
Descriptor	ACETYL-COA--DEACETYLCEPHALOSPORIN C ACETYLTRANSFERASE, 4-(3-ACETOXYMETHYL-2-CARBOXY-8-OXO-5-THIA-1-AZA-BICYCLO[4.2.0]OCT-2-EN-7-YLCARBAMOYL)-1-CARBOXY-BUTYL-AMMONIUM, ACETATE ION, ... (4 entities in total)
Functional Keywords	deacetylcephalosporin c, cephalosporin biosynthesis, a/b-hydrolase fold, antibiotic biosynthesis, transferase, acyltransferase, acetyl transferase
Biological source	ACREMONIUM CHRYSOGENUM
Total number of polymer chains	12
Total formula weight	596703.52
Authors	Lejon, S.,Ellis, J.,Valegard, K. (deposition date: 2007-09-04, release date: 2008-09-23, Last modification date: 2011-07-13)
Primary citation	Lejon, S.,Ellis, J.,Valegard, K. The Last Step in Cephalosporin C Formation Revealed: Crystal Structures of Deacetylcephalosporin C Acetyltransferase from Acremonium Chrysogenum in Complexes with Reaction Intermediates. J.Mol.Biol., 377:935-, 2008 Cited by PubMed: 18279889 DOI: 10.1016/J.JMB.2008.01.047 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation