2V8X

Crystallographic and mass spectrometric characterisation of eIF4E with N7-cap derivatives

2V8X の概要

• エントリーDOI: 10.2210/pdb2v8x/pdb
• 関連するPDBエントリー: 1IPB 1IPC 2JGB 2JGC 2V8W 2V8Y
• 分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1, 7-BENZYL GUANINE MONOPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: translation, phosphorylation, initiation factor, cap, eif4e, 7bngmp, 4e-bp1, rna-binding, acetylation, host-virus interaction, protein synthesis inhibitor, protein biosynthesis, translation regulation
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 54891.67

構造登録者

Brown, C.J.,Mcnae, I.,Fischer, P.M.,Walkinshaw, M.D. (登録日: 2007-08-16, 公開日: 2007-08-28, 最終更新日: 2023-12-13)

• 主引用文献: Brown, C.J.,Mcnae, I.,Fischer, P.M.,Walkinshaw, M.D.; Crystallographic and Mass Spectrometric Characterisation of Eif4E with N(7)-Alkylated CAP Derivatives.; J.Mol.Biol., 372:7-, 2007; PubMed: 17631896; DOI: 10.1016/J.JMB.2007.06.033

実験手法

X-RAY DIFFRACTION (2.3 Å)