2V74

Crystal structure of coactivator-associated arginine methyltransferase 1 (CARM1), in complex with S-adenosyl-homocysteine

Summary for 2V74

Entry DOI	10.2210/pdb2v74/pdb
Descriptor	HISTONE-ARGININE METHYLTRANSFERASE CARM1, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
Functional Keywords	arginine methyltransferase, s-adenosyl-l-methionine, transcription regulation, alternative splicing, histone modification, co- activator, methyltransferase, chromatin regulator, nucleus, cytoplasm, transferase, transcription
Biological source	MUS MUSCULUS (MOUSE)
Cellular location	Nucleus: Q9WVG6
Total number of polymer chains	4
Total formula weight	157955.97
Authors	Yue, W.W.,Hassler, M.,Roe, S.M.,Thompson-Vale, V.,Pearl, L.H. (deposition date: 2007-07-26, release date: 2007-10-02, Last modification date: 2024-02-14)
Primary citation	Yue, W.W.,Hassler, M.,Roe, S.M.,Thompson-Vale, V.,Pearl, L.H. Insights Into Histone Code Syntax from Structural and Biochemical Studies of Carm1 Methyltransferase Embo J., 26:4402-, 2007 Cited by PubMed: 17882261 DOI: 10.1038/SJ.EMBOJ.7601856 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation