2V2V

IspE in complex with ligand

2V2V の概要

• エントリーDOI: 10.2210/pdb2v2v/pdb
• 関連するPDBエントリー: 2V2Q 2V2Z 2V34 2V8P 2VF3
• 分子名称: 4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL KINASE, SULFATE ION, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: transferase, 4-diphosphocytidyl-2c-methyl-d- erythritol, aquifex aeolicus, nucleotide-binding, isoprene biosynthesis, kinase, atp-binding, non-mevalonate
• 由来する生物種: AQUIFEX AEOLICUS
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 62397.36

構造登録者

Alphey, M.S.,Hunter, W.N. (登録日: 2007-06-07, 公開日: 2007-06-19, 最終更新日: 2024-05-08)

• 主引用文献: Crane, C.M.,Hirsch, A.K.,Alphey, M.S.,Sgraja, T.,Lauw, S.,Illarionova, V.,Rohdich, F.,Eisenreich, W.,Hunter, W.N.,Bacher, A.,Diederich, F.; Synthesis and Characterization of Cytidine Derivatives that Inhibit the Kinase Ispe of the Non-Mevalonate Pathway for Isoprenoid Biosynthesis.; Chemmedchem, 3:91-, 2008; PubMed: 18033714; DOI: 10.1002/CMDC.200700208

実験手法

X-RAY DIFFRACTION (2.4 Å)