2SRC

CRYSTAL STRUCTURE OF HUMAN TYROSINE-PROTEIN KINASE C-SRC, IN COMPLEX WITH AMP-PNP

Summary for 2SRC

Entry DOI	10.2210/pdb2src/pdb
Descriptor	TYROSINE-PROTEIN KINASE SRC, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER (3 entities in total)
Functional Keywords	src, tyrosine-protein kinase, phosphorylation, sh2, sh3, phosphotyrosine, proto-oncogene, phosphotransferase
Biological source	Homo sapiens (human)
Cellular location	Cell membrane: P12931
Total number of polymer chains	1
Total formula weight	52215.77
Authors	Xu, W.,Doshi, A.,Lei, M.,Eck, M.J.,Harrison, S.C. (deposition date: 1998-12-29, release date: 1999-07-22, Last modification date: 2023-08-09)
Primary citation	Xu, W.,Doshi, A.,Lei, M.,Eck, M.J.,Harrison, S.C. Crystal structures of c-Src reveal features of its autoinhibitory mechanism. Mol.Cell, 3:629-638, 1999 Cited by PubMed: 10360179 DOI: 10.1016/S1097-2765(00)80356-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation