2SRC
CRYSTAL STRUCTURE OF HUMAN TYROSINE-PROTEIN KINASE C-SRC, IN COMPLEX WITH AMP-PNP
Summary for 2SRC
Entry DOI | 10.2210/pdb2src/pdb |
Descriptor | TYROSINE-PROTEIN KINASE SRC, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER (3 entities in total) |
Functional Keywords | src, tyrosine-protein kinase, phosphorylation, sh2, sh3, phosphotyrosine, proto-oncogene, phosphotransferase |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane: P12931 |
Total number of polymer chains | 1 |
Total formula weight | 52215.77 |
Authors | Xu, W.,Doshi, A.,Lei, M.,Eck, M.J.,Harrison, S.C. (deposition date: 1998-12-29, release date: 1999-07-22, Last modification date: 2023-08-09) |
Primary citation | Xu, W.,Doshi, A.,Lei, M.,Eck, M.J.,Harrison, S.C. Crystal structures of c-Src reveal features of its autoinhibitory mechanism. Mol.Cell, 3:629-638, 1999 Cited by PubMed: 10360179DOI: 10.1016/S1097-2765(00)80356-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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