2SHP

TYROSINE PHOSPHATASE SHP-2

Summary for 2SHP

• Entry DOI: 10.2210/pdb2shp/pdb
• Descriptor: SHP-2, DODECANE-TRIMETHYLAMINE (3 entities in total)
• Functional Keywords: tyrosine phosphatase, insulin signaling, sh2 protein
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q06124
• Total number of polymer chains: 2
• Total formula weight: 120820.73

Authors

Hof, P.,Pluskey, S.,Dhe-Paganon, S.,Eck, M.J.,Shoelson, S.E. (deposition date: 1997-12-01, release date: 1999-02-16, Last modification date: 2024-04-03)

• Primary citation: Hof, P.,Pluskey, S.,Dhe-Paganon, S.,Eck, M.J.,Shoelson, S.E.; Crystal structure of the tyrosine phosphatase SHP-2.; Cell(Cambridge,Mass.), 92:441-450, 1998; PubMed: 9491886; DOI: 10.1016/S0092-8674(00)80938-1

Experimental method

X-RAY DIFFRACTION (2 Å)