2RQU
Solution structure of the complex between the DDEF1 SH3 domain and the APC SAMP1 motif
Summary for 2RQU
Entry DOI | 10.2210/pdb2rqu/pdb |
Related | 2RQT |
NMR Information | BMRB: 11082 |
Descriptor | DDEF1_SH3, 19-mer from Adenomatous polyposis coli protein (2 entities in total) |
Functional Keywords | sh3 domain, gap, samp motif, tumor suppressor, cell junction, disease mutation, phosphoprotein, wnt signaling pathway, signaling protein |
Biological source | Homo sapiens More |
Cellular location | Cytoplasm (By similarity): Q9ULH1 Cell junction, adherens junction: P25054 |
Total number of polymer chains | 2 |
Total formula weight | 9117.31 |
Authors | Kaieda, S.,Matsui, C.,Mimori-Kiyosue, Y.,Ikegami, T. (deposition date: 2009-12-14, release date: 2010-07-07, Last modification date: 2024-05-01) |
Primary citation | Kaieda, S.,Matsui, C.,Mimori-Kiyosue, Y.,Ikegami, T. Structural basis of the recognition of the SAMP motif of adenomatous polyposis coli by the Src-homology 3 domain. Biochemistry, 49:5143-5153, 2010 Cited by PubMed: 20509626DOI: 10.1021/bi100563z PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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