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2RQU

Solution structure of the complex between the DDEF1 SH3 domain and the APC SAMP1 motif

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DDEF1_SH3polymer617066.81UniProt (Q9ULH1)
Pfam (PF14604)
Homo sapiensDDEF1_SH3, 130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein, PIP2-dependent ARF1 GAP, ADP-ribosylation factor-directed GTPase-activating protein 1, ARF GTPase-activating protein 1, Development and differentiation-enhancing factor 1, Differentiation-enhancing factor 1, DEF-1
2B
(B)
19-mer from Adenomatous polyposis coli proteinpolymer192050.51UniProt (P25054)
Pfam (PF05924)
Homo sapiens (human)Protein APC, Deleted in polyposis 2.5
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight9117.3
All*Total formula weight9117.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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